Influence of CO2 on brain activity and metabolism in conscious humans
Our observation of a reduced functional connectivity during CO2 breathing is consistent with previous reports that light sedation (Greicius et al, 2008) or anesthesia (Deshpande et al, 2010) decreases connectivity in DMN regions, and is also in line with the suggestions that CO2 has a mild sedative effect (Fukuda et al, 2006).
